This project is a program focused on improving educator effectiveness through increasing teachers’ mathematics and science content knowledge in ways that support inquiry-based instruction which integrates both disciplines. The project approach holds as a central premise that all teachers are capable of engaging students in meaningful mathematics and science activity. However, developing the knowledge and skills to instruct effectively requires significant investment of time and resources on the part of the teacher, professional developers and the school community. As such, this project approach helps teachers develop the necessary knowledge and skills to effectively design instruction that integrates core disciplinary concepts (namely mathematics and science content) to solve problems that are of both local and global significance and that are also personally meaningful to students. The Center for P-16 Research and Collaboration at Indiana University’s School of Education facilitates the project among elementary school teachers and faculty from Indiana University-Bloomington’s School of Education, Gary Community School Corporation, School City of East Chicago, and School City of Hammond.